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Weight Loss

Semaglutide, Insulin and Weight Loss

Here is a Link to Dr CS Talking about this

Semaglutide was recently approved by the FDA to treat obesity under the brand name Wegovy.  This study published in the New England Journal of Medicine shows why.  The average person lost 14.9% of their body mass or 33.7 lbs.  Which is pretty impressive but how does it work?

https://www.nejm.org/doi/full/10.1056/NEJMoa2032183

Semaglutide is a Glucagon Like Peptide or GLP-1 that helps your body be more effective at insulin secretion and managing blood glucose levels.

Why would being more efficient at insulin secretion help you lose body fat?  Insulin is a hormone that tells your body to store energy.  It signals your organs / cells to pull glucose from the blood stream and store it.

Glucose/glycogen is a form of energy or currency and insulin is a message to store that energy or not to spend that currency.  

If we look at people who suffer from diseases where they cannot make insulin, without intervention they get skinnier and skinnier until they die regardless of how much they eat.  

If we look at diseases where the patient makes too much insulin, most are just getting fatter and fatter overtime.

Most overweight Americans have in the course of their life over consumed processed carbohydrates and their internal environment suffers from too much insulin.  They need help getting back to normal.  This is why lower carb and fasting can be helpful for losing weight, both those strategies would lower insulin production.  Semaglutide helps your body be better at insulin production so you make the right amount of it at the right time.  It helps your liver and pancreas work better.  It really helps with cravings and feeling full or satiated.  All of which helps with losing body fat.

This totally is consistent with what we have been teaching at Slim Rx for the last 6 years.  We have been focused on creating a low insulin / low cortisol lifestyle 5 days a week.

The right amount of insulin = Lean and healthy

Too much insulin = Overweight / higher body fat

Our strategy of 2 meals a day, less then 80 grams of carbs in an eating window 5 days a week helps create a low insulin internal environment for you which will help you burn fat and lean out.

Semaglutide has been used for years to help type 2 diabetics lower their A1C.  It is sold under the brand names Ozempic and Rybelsus.  It does a pretty good job of lowering patients A1C it also appears to do a good job of helping some patients lose weight.  I’m personally excited about the potential for it and there is a lot of buzz among weight loss professionals about how this is going to work for patients and change the industry.

Insulin has a lot to do with whether you are storing fat or burning fat.  A low insulin lifestyle can not only help you burn fat but it is a good healthy long term strategy.

If you want to know more or are interested in Semaglutide or Wegovy we can set you up with a consultation with Amy or Dr Lovegrove to see if it is medically appropriate for you.